The AWS-powered research engine helped Moderna deliver the first clinical batch of its COVID-19 vaccine candidate, mRNA-1273. Moderna has been able to quickly design research experiments and uncover new insights, automate laboratory and manufacturing processes, and comply with laws and regulations using Amazon's services.

Moderna has developed proprietary technologies and methods that run on AWS to create its mRNA constructs. Moderna's Drug Design Studio allows the company to quickly design mRNA sequences for various protein targets, followed by analytics and machine learning to optimize the sequences for production and subsequent physical testing. Amazon Redshift, AWS's fully managed data warehousing service, is being used to aggregate results from dozens of experiments being run in parallel. Moderna scientists and engineers can easily query and share insights to refine designs and production.

Moderna's automated production facility utilizes AWS internet-of-things services to connect instruments, robotics, and other critical systems for ease of manufacturing tracing. AWS can also be used to essentially copy and paste Moderna's digital manufacturing model to partner facilities for technology transfer, providing rapid access to additional production capacity.

Animal study turns in positive results for Moderna-NIH COVID-19 vaccine
Moderna's COVID-19 vaccine candidate, messenger RNA (mRNA)-1273, has been shown to induce immune responses and control upper and lower respiratory tract...

Moderna begins phase III testing of COVID-19 vaccine
Moderna has begun a phase III clinical trial evaluating its messenger RNA (mRNA)-1273 COVID-19 vaccine candidate. The trial is expected to enroll approximately...

Moderna reports positive results in COVID-19 vaccine trial
Moderna is reporting positive results with a COVID-19 vaccine candidate it is developing. The candidate, messenger RNA (mRNA)-1273, was safe and triggered...

Catalent to provide fill-finish for Moderna's COVID-19 vaccine
Catalent will collaborate with Moderna for large-scale commercial fill-finish manufacturing of Moderna's messenger RNA-based COVID-19 vaccine candidate,...

Moderna moves COVID-19 vaccine to late-stage clinical trial
Moderna has finalized phase III clinical study protocols for its mRNA-1273 COVID-19 vaccine candidate in coordination with the U.S. Food and Drug Administration...