The collection is composed of gene-edited human induced pluripotent stem cell lines developed using CRISPR/Cas9 technology. The collection is ideal for live cell imaging to capture organelle dynamics and function in normal and disease models. Across the cell lines, 33 unique cellular structures have been tagged. With dual- and triple-edited cell lines, several key structures can be highlighted within the same cell.

With this extension, the Allen Institute will make the collection available to academic researchers and commercial entities.

The Coriell Institute for Medical Research will hold the cell lines in their biobanks. They will provide services in pipeline development with an emphasis on quality control and assessing the genomic, structural, and pluripotency integrity of cells.