Avacta's Affimer reagent may neutralize SARS-CoV-2

By The Science Advisory Board staff writers

May 15, 2020 -- Avacta Group, the developer of Affimer biotherapeutics and reagents, announced that several Affimer reagents block the interaction between SARS-CoV-2's spike protein and angiotensin-converting enzyme 2 (ACE2), a receptor on human cells that is key to the virus infection pathway.

This mechanism thus has the potential to prevent infection and act as a neutralizing therapy, the firm said. The reagents could be given to individuals who have been exposed to the virus to prevent infection, as well as to COVID-19 patients already infected by the virus. Avacta is looking for a partner with resources to develop the neutralizing therapy as quickly as possible.

As part of its partnership with Cytiva (formerly GE Healthcare Life Sciences and now part of Danaher), the firm has already developed a large number of Affimer reagents that bind to the SARS-CoV-2 virus's spike protein. The two firms are working on a rapid point-of-care COVID-19 antigen saliva test to be mass produced for large-scale population screening and for self-testing by consumers.


Copyright © 2020 scienceboard.net
 

Create an Account

Already have an account? Sign in Here

To access all ScienceBoard content create a free account now:



Email Address:  

First Name:

Last Name:

Learn about ScienceBoard

Get the latest life sciences research and industry news, delivered straight to your inbox, for free.

Why subscribe?

ScienceBoard is uniquely focused on the business of research, addressing the biggest problems that the biomedical industry face. You’ll get breaking news, events coverage, and deep dives into the science that drives innovation, delivered to your inbox daily.

 
I have read and agree to the privacy policy and terms of service and wish to opt-in for ScienceBoard.net.

Email Preferences



Letter from the Editor Please send me twice-weekly roundups of all the latest life research and industry news.
SAB Announcements Please send me the latest announcements from The Science Advisory Board and their partners.
Spotlight Receive notifications about new content, services, or educational resources designed to help you sharpen your skills and grow professionally.