Twist Bioscience purchases library designed with Distributed Bio

By The Science Advisory Board staff writers

April 12, 2021 -- Twist Bioscience plans to exercise its option to purchase all rights to a G-coupled protein receptor (GPCR) library and its Twist antibody optimization software, both of which it developed in collaboration with Distributed Bio.

The library and the software were originally built as part of a 2016 license agreement between Twist Bioscience and Distributed Bio, according to the firm. Twist has been using the GPCR library and software together with its silicon-based DNA synthesis platform for the past two years to enable synthetic DNA writing oligo pool technology.

Building on the GPCR library, Twist Biopharma, a division of Twist Bioscience, generated a wide range of precision antibody discovery libraries, which now are encompassed in what the firm calls its "library of libraries," containing antibody fragment scaffolds as well as different sources of fully human antibody sequences.

Once binding antibodies are identified from the library of libraries or other sources, Twist Biopharma utilizes the Twist antibody optimization software and its custom library capacity to further optimize leads for improved pharmacokinetic, pharmacodynamic, binding, and other properties.

Financial terms of the agreement were not disclosed.

Copyright © 2021

Create an Account

Already have an account? Sign in Here

To access all ScienceBoard content create a free account now:

Email Address:  

First Name:

Last Name:

Learn about ScienceBoard

Get the latest life sciences research and industry news, delivered straight to your inbox, for free.

Why subscribe?

ScienceBoard is uniquely focused on the business of research, addressing the biggest problems that the biomedical industry face. You’ll get breaking news, events coverage, and deep dives into the science that drives innovation, delivered to your inbox daily.

I have read and agree to the privacy policy and terms of service and wish to opt-in for

Email Preferences

Letter from the Editor Please send me twice-weekly roundups of all the latest life research and industry news.
SAB Announcements Please send me the latest announcements from The Science Advisory Board and their partners.
Spotlight Receive notifications about new content, services, or educational resources designed to help you sharpen your skills and grow professionally.