Simulations Plus, Univ. of Pittsburgh partner to evaluate large-molecule drugs

By The Science Advisory Board staff writers

February 23, 2021 -- Medical simulation software company Simulations Plus and the University of Pittsburgh Drug Discovery Institute (UPDDI) have jointly received a phase I grant from the U.S. National Institutes of Health (NIH)-funded Small Business Innovation Research (SBIR) grant to support their large-molecule safety collaboration.

As a result of the funding from the NIH, Simulation Plus' Dilisym Services (DSS) division will combine its software with UPDDI's biomimetic human liver microphysiological systems (vLAMPS) experimental liver model and the microphysiology systems database to predict the safety of large molecules such as proteins for treating diseases.

In the first phase of the project, a beta version of software will be constructed and vLAMPS testing will be performed for several large molecules captured in the database. If the objectives are successfully completed, Simulation Plus and UPDDI will then apply for a larger phase II grant to fully fund development of a joint commercial offering, they said.

Copyright © 2021

Create an Account

Already have an account? Sign in Here

To access all ScienceBoard content create a free account now:

Email Address:  

First Name:

Last Name:

Learn about ScienceBoard

Get the latest life sciences research and industry news, delivered straight to your inbox, for free.

Why subscribe?

ScienceBoard is uniquely focused on the business of research, addressing the biggest problems that the biomedical industry face. You’ll get breaking news, events coverage, and deep dives into the science that drives innovation, delivered to your inbox daily.

I have read and agree to the privacy policy and terms of service and wish to opt-in for

Email Preferences

Letter from the Editor Please send me twice-weekly roundups of all the latest life research and industry news.
SAB Announcements Please send me the latest announcements from The Science Advisory Board and their partners.
Spotlight Receive notifications about new content, services, or educational resources designed to help you sharpen your skills and grow professionally.