Cancer researchers publish study on avidity enhancement of CAR T cells May 25, 2022 -- A team of cancer researchers led by Dr. Marcela Maus have published a preclinical study detailing the use of the Lumicks z-Movi Cell Avidity Analyzer to provide more nuanced development of cancer treatments. The study focused on using Lumicks’ technology to identify chimeric antigen receptor (CAR) T cells that are best suited to treat acute myeloid leukemia.Read More
Next-generation AAV capsids hold key to developing life-changing therapies May 24, 2022 -- Voyager Therapeutics’ discovery platform is identifying novel capsids targeting desired cells and tissues with greater specificity, at lower doses, and with fewer off-target risks than conventional adeno-associated virus (AAV) serotypes in non-human primates, according to Todd Carter, PhD, senior vice president for research. The company presented data on the platform at the American Society of Gene & Cell Therapy 2022 annual meeting.Read More
Researchers discover what causes cancer cells to eat proteins September 13, 2022 -- European researchers have identified the molecular pathway that allows cancer cells to start breaking down surrounding proteins as a food source when facing starvation. The discovery has implications for cancer research and treatment.Read More
Mount Sinai scientists unlock secrets of key SARS-CoV-2 enzyme September 12, 2022 -- Mount Sinai researchers have produced a high-resolution crystal structure of an enzyme that is essential to the survival of SARS-CoV-2. The finding could lead to more antivirals to combat current and future coronaviruses, they added.Read More
Research unveils opioid-receptor structure July 25, 2022 -- A preclinical study shows in vitro evidence that reveals the preference of certain receptors to form homodimeric complexes and tetrameric complexes, which relates to the addictive effects of opioids.Read More
Study of T-cell behavior predicts therapeutic differences in cancer outcomes May 10, 2022 -- Researchers at Weill Cornell Medicine have published a study in Cancer Cell revealing a novel insight on the role of T cells in cancer therapies. The study focused on comparing the differences in behaviors of T cells in immunotherapy for metastatic melanoma to treatment outcomes.Read More