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Novel strategy for studying mitoribosomal and mitochondrial impact on disease
November 5, 2019 -- Researchers from the Karolinska Institutet in Sweden have developed a new experimental tool for studying mitochondrial protein synthesis in vivo. This research is presented in the October 5 issue of Cell Reports.  Discuss
Cutting edge microscopy technique leads to new insights in cancer
November 1, 2019 -- New research published in the October 31 edition of Science debuts a new technique for creating high-resolution visual maps of the chromatin structure remodeling (RSC) complex to further understand its role in healthy and cancer cells. This research was led by Bradley Cairn, PhD, cancer researcher at Huntsman Cancer Institute and professor and chair of oncological sciences at the University of Utah.  Discuss
Orphan immunity gene clusters acquired for protection
October 30, 2019 -- Researchers from the University of Washington School of Medicine and Howard Hughes Institute found that gut bacteria acquire interbacterial defense gene clusters. The October 30 article in Nature, suggests that bacteria use these toxins against their microbial neighbors. This discovery could further scientific knowledge of the human gut which is critical to many aspects of health and disease.  Discuss
New model uses bioinformatics to identify aggressive breast cancers
October 29, 2019 -- Researchers from the University of Bonn propose a new method to determine the prognosis of disease using the patients' tumor tissue. The results were published in Cell Reports on October 29.  Discuss
Immune cells shown to kill MRSA before it enters the body
October 29, 2019 -- Neutrophils could be responsible for controlling bacterial numbers of an antibiotic-resistant strain of Staphylococcus aureus (MRSA) on human skin before the bacteria get a chance to invade, according to a new study from Karolinska Institutet published in Cell Reports on October 29.  Discuss
Better flu treatments on the way thanks to the discovery of broadly protective antibodies
October 28, 2019 -- Research from the National Institutes of Allergy and Infectious Diseases (NIAID) isolated the antibodies from a person sick with the flu five days after onset. They isolated antibodies that bind to neuraminidase (NA) proteins on the surface of influenza viruses, which provided broad protection against several different strains of influenza both in vitro and in vivo. The researchers provided characterization details in the October 25 issue of Science.  Discuss
Researchers identify microproteins with major implications in disease
October 25, 2019 -- A new study published in Nature Communications on October 25 provides evidence of how microproteins contribute to cellular stress. Researchers from Salk Institute suggest that these small proteins can cause dysregulation, which underlies several debilitating diseases including cancer, neurodegenerative disorders, and diabetes.  Discuss
New insights into why tumor suppressor proteins go awry in cancer
October 23, 2019 -- Researchers from Stowers Institute for Medical Research in Kansas City, MO have identified proteins that are involved in tumor growth and metastasis in many cancers such as breast cancer. The research was published in Science Advances on October 23.  Discuss
Innovations in 3D printing lead to implantable blood vessels
October 22, 2019 -- Using bioinks formulated from smooth muscle cells from a human aorta and endothelial cells from an umbilical vein, researchers built a biomimetic blood vessel using 3D printing techniques.  Discuss
Night gardeners: Microglia involved in brain plasticity during sleep
October 21, 2019 -- Research from the University of Rochester Medical Center (URMC) suggests that specific immune cells called microglia – which play a crucial role in reorganizing connections between nerve cells, fighting infection, and repairing damage – are primarily active during sleep. The research, conducted on mouse models, was published in Nature Neuroscience on October 21.  Discuss
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