Life Science Informatics
Computer tools shorten development time for SARS-CoV-2 drugs
Computer-based tools are helping researchers find potentially promising candidates for vaccines and treatments for SARS-CoV-2 -- and much more quickly than traditional approaches. Many of these software tools are described in an article published June 24 in Science Advances.  Discuss
New platform includes biological similarities to accelerate drug discovery
A new open-access tool provides information on the effects of nearly 1 million compounds in a wide range of biological settings. The new tool, published in Nature Biotechnology on May 18, may change the drug discovery process by moving beyond reliance on chemical information alone.  Discuss
Scientists explore SARS-CoV-2 main protease as a drug target
A team of researchers report the structure of the main protease of the novel coronavirus and have identified several drugs that show promise in combating the virus, according to an April 9 article published in Nature.  Discuss
How AI is speeding development of COVID-19 therapies
As the world is facing a new challenge in trying to both adapt to and defend itself against the novel coronavirus, artificial intelligence (AI) is offering new hope that a cure might be developed faster than ever before. Ulrik Kristensen, PhD, from Signify Research offers a perspective.  Discuss
3D magnetic cell culture transforms cancer therapy screening
Traditional high-throughput drug screening in oncology routinely relies on 2D cell models, which inadequately recapitulate the physiologic context of cancer. With recent technological advancements, a novel method for magnetic 3D cell culture can create pancreatic tumor models. This model may have serious effects on cancer research.  Discuss
Artificial intelligence helps researchers find new antibiotics
To address antibiotic resistance, researchers have developed a machine-learning approach that can search millions of known chemicals to find new potential antimicrobial compounds. This research, published in Cell on February 20, uncovered several promising antibiotic candidates that will move into clinical testing.  Discuss
New synthetic vaccine fights infectious disease with assistance from the data cloud
A new synthetic vaccine developed by researchers at the University of Bristol and the French National Centre for Scientific Research can be stored at warmer temperatures due to an engineered scaffold design. The details of the Chikungunya vaccine candidate are published in Science Advances on September 25.  Discuss
Biologically active molecules in coal are found to have antiviral properties against tick-borne encephalitis
Scientists from Russia demonstrated in a Scientific Reports article published on August 19, that biologically active molecular components of substances extracted from coal, humic substances, have antiviral properties. A novel approach to identify these molecules determined that these molecules inhibit the reproduction of tick-borne encephalitis virus (TBEV), which causes clinically relevant human viral infectious disease.  Discuss
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Conferences
BioProcess International Europe
July 13-17
Central European Time Zone (CET) Netherlands
2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States
Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States
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