Immunology Sponsored by Beckman Coulter
COVID-19 vaccine candidates show progress amid challenges
As the COVID-19 outbreak advances worldwide, companies are stepping up to the challenge to develop a potential vaccine. There are over 75 confirmed COVID-19 vaccine candidates, five of which have already entered clinical trials.  Discuss
The jury is still out for SARS-CoV-2 intermediate host
Scientists have been searching for the intermediate host between bats, which are known to carry coronaviruses, and the first introduction of SARS-CoV-2 into humans. Conflicting research argues the merit of dogs as intermediate hosts of the virus.  Discuss
Could a MERS vaccine candidate be the answer for COVID-19?
As researchers urgently work to develop vaccines to prevent COVID-19, many strategies have been considered. Now, a parainfluenza virus 5-based vaccine expressing MERS-CoV spike protein may provide an avenue for a COVID-19 vaccine based on the similarity of the two viruses, according to a study published in mBio on April 7.  Discuss
3 reasons the coronavirus outbreak has been so severe
WASHINGTON, DC - Why has the current outbreak of coronavirus been so severe compared with past epidemics of viral respiratory diseases? It has to do with unique characteristics of the coronavirus itself, according to a speaker at a February 26 congressional briefing.  Discuss
Breakthrough in coronavirus research provides map for vaccines
Critical research reveals the 3D atomic-scale map of the spike protein of the 2019 novel coronavirus (2019-nCoV), which is responsible for infecting humans. This breakthrough will aid in the development of vaccines and antiviral drugs to combat the spread of the virus. The research was published in Science on February 19.  Discuss
Personalized cancer vaccines now possible due to discovery of cancer frameshift neoantigens
Researchers from Arizona State University's Biodesign Institute demonstrated experimental proof-of-concept that cancer mutations produce individual neoantigens, or newly formed antigens, and can be used for cancer vaccines. The new paper published in Scientific Reports on October 2, shows that neoantigens can be used to protect against cancer.  Discuss
New synthetic vaccine fights infectious disease with assistance from the data cloud
A new synthetic vaccine developed by researchers at the University of Bristol and the French National Centre for Scientific Research can be stored at warmer temperatures due to an engineered scaffold design. The details of the Chikungunya vaccine candidate are published in Science Advances on September 25.  Discuss
Vaccine in development against hypervirulent Klebsiella
Concerns arising over the development of hypervirulent strains of Klebsiella pneumoniae have led researchers to develop an entirely new vaccine to protect against the gram-negative bacteria. A team of researchers at Washington University School of Medicine in St. Louis and VaxNewMo (a startup based in St. Louis) designed the vaccine by genetically manipulating E. coli. The details of the prototype designed were published in the Proceedings of the National Academy of Sciences on August 27th.  Discuss
Thermally stable TB vaccine may now be possible thanks to an innovative new process
Researchers at the University of Bath have developed a process that protects vaccines from heat damage by trapping them in silica cages. The results were published in Scientific Reports on August 8, 2019. Using a leading candidate in the development on new vaccines, Ag85b in conjunction with adjuvant Sbi-Ag85b, thermal stability of tested using a novel process called ensilication.  Discuss
Structure-based vaccine design may help save the lives of infants and children
A new experimental vaccine, utilizing structure-based design, shows promise in a phase I clinical trial. The vaccine will protect against respiratory syncytial virus (RSV), a leading cause of infectious disease deaths in infants. Researchers at the University of Texas at Austin published findings on Aug 2, 2019 in Science stating that one dose elicited increases in RSV-neutralizing antibodies over several months.  Discuss
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January 28-29, 2021
London, Greater London United Kingdom
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May 11-12, 2021
Boston, Massachusetts United States
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