Genomics
Zigzag DNA provides insight into chromosome organization
New Z-loops -- DNA folded into a zigzag structure and guided by essential condensin proteins -- have been caught on camera for the first time. The results of the study provide insight into the organization of chromosomes and were published in Nature on March 4. Read More
New coronavirus puts focus on the science of naming new viruses
What's in a name? Possibly a lot, when it comes to determining how to name new virus species based on genetic characteristics. The initial confusion over the naming of the novel coronavirus indicates that the scientific community still has work to do when defining the proper taxonomy of viruses, according to an article published in Nature Microbiology on March 2. Read More
Glia-to-neuron conversion gene therapy can treat Huntington's disease
Using adeno-associated virus technology, researchers have developed a novel gene therapy that can regenerate functional neurons in mouse models of Huntington's disease. The work was published in Nature Communications on February 27. Read More
Extra copies of chromosomes can be good or bad
Researchers are developing human cell lines to explore how extra copies of chromosomes can enhance the metastasis and invasiveness of cancer cells. They explained their methodology in a study published in Developmental Cell on February 24. Read More
New NIH study pinpoints how coronavirus attacks cells
The continued spread of the novel 2019 coronavirus, known as SARS-CoV-2, around the world has raised the need for a test to rapidly and efficiently screen coronaviruses to monitor rapid changes and determine how they function. Findings from ongoing U.S. National Institutes of Health (NIH) research, published in Nature Microbiology on February 24, offer new tools in the fight. Read More
Genomic landscape of osteosarcomas reveals why immunotherapy may not be effective
Immune profiling of osteosarcoma has revealed why immune checkpoint inhibitors might not be an effective treatment option for patients with this rare type of cancer, according to new research published online February 21 in Nature Communications. Read More
Communication of cancer cells analyzed with organoids and novel cytometry
A new technique using organoids, self-organizing 3D tissue models, can decipher how individual cancer cells communicate with each other and the unique signals they create. This research, published in Nature Methods on February 17, could be used to help develop personalized cancer treatments in the future. Read More
Phages containing huge amounts of DNA are found around the globe
An inventory of over 350 DNA sequences from phage genomes revealed that these genomes can be over 200,000 base pairs in length and found the largest phage genome ever described at 735,000 base pairs in length. The report published in Nature on February 12, evaluated the prevalence, diversity and ecosystem distribution of phages with large genomes. Read More
CRISPR proteins developed for use in molecular diagnostics
New CRISPR technology is being developed as a molecular diagnostic tool with the capability of detecting unique disease biomarkers. Eventually, these at-home tests will allow patients to conduct at-home diagnostic tests quickly. Read More
Genomics sheds light on the life history of cancers
As part of a special collection of papers on pan-cancer analysis of whole genomes published online by Nature on February 6, an international group of scientists analyzed over 2,500 unique cancer genomes to shed light on the life history of cancer mutations and how cancer tumors evolve -- even before they are diagnosed. Read More
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September 27-28
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Infectious Diseases (ID) Week 2021
September 29 - October 3
San Diego, California United States
Imaging Mass Spectrometry Society (IMSS) 3 in 2021
October 3-6
Colorado Springs, Colorado United States
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October 10-14
Carlsbad, California United States
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