Genomics
Improving the CRISPR-Cas9 Workflow
Following the insights gained from past research, we fielded a survey to our expert panel of scientists to quantify how the emergence of CRISPR is impacting the use of traditional tools and techniques. In this article, we are revealing some verbatim answers from the questionnaire.  Discuss
Tech Overview - Time of Flight Mass Spectrometry
If you have been following our mass spec series you have certainly recognized the number of different ways mass spec can be used to separate ions of different masses. Time of Flight Mass Spectrometry (TOF-MS) was developed in the 1940’s and began to gain popularity in the 1990’s. Since then, the technology has been enhanced and updated to be the device we have today.  Discuss
The “Two-Headed Monster”: Vendors Tackle Antibody Validation
The Science Advisory Board examined the preferences of scientists regarding the purchase and use of antibodies, as well as customer trust, satisfaction, and "best-in-class" vendors in the sector. Respondents also made comments detailing their ideas on reproducible research using antibodies, the responsibilities of both vendors and researchers when it comes to using commercial antibodies, and much more.  Discuss
Next Generation Sequencing Data: Tertiary Analysis
As Next Generation Sequencing (NGS) technology develops, the analysis and interpretation of NGS data will prove to be one of the most complex aspects of transforming NGS data into meaningful results. Tertiary analysis, which follows primary and secondary analysis of the data, is among the most challenging steps.  Discuss
Compact Image-Based Cell Analyzers
At The Science Advisory Board, we have the opportunity to explore many different types of research technology on behalf of our scientific community. In this article we discuss the $50 million market for compact image-based cell analyzers. Broadly, cytometers refer to instruments that can measure various characteristics of cell populations in suspension. Depending on which and how many characteristics or parameters they address, these systems can be classified differently.  Discuss
NGS Informatics: Choosing the Superior Software Tool
As Next Generation Sequencing (NGS) continues to grow, scientists face many challenges in terms of their data analysis and storage solutions. Our members at The Science Advisory Board have disclosed it is difficult to determine the significance of results as well as store the mass amounts of data. There are many solutions but most lack desired features, creating uncertainty amongst researchers over the best option.  Discuss
CRISPR - A New Era in Genome Editing
A major buzzword in the science world recently has been CRISPR: short for Clustered Regularly Interspaced Short Palindromic Repeats. This is a simple, yet powerful genome-editing technique that has recently taken the scientific community by storm. When coupled with the Cas9 protein, the technology allows for specific changes (addition, modification, and deletions) to be made to the DNA of humans, animals, and plants, thereby offering a tremendous potential in a wide array of applications from agriculture biotechnology to therapeutics.  Discuss
Competition within Single-Cell Analysis Technology
The excitement surrounding the ability to measure genomic, epigenomic, transcriptomic, and metabolic status in individual cells is reflected in the high level of activity we’ve seen this past year. We at The Science Advisory Board are excited to share with our members some of the highlights we’ve observed within single-cell analysis this past year.  Discuss
Rise of Genomics Spurs Innovation in Instruments & Techniques
The global advance of health care increasingly depends on the study of genetics and the human genome. From determining the genetic composition of a tumor to revealing rare genetic disorders in newborns, innovative technologies and techniques have given us the ability to diagnose and monitor a patient’s disease, assess their health risk, and decide which remedies are best suited for prevention or treatment.  Discuss
Researchers Speak Out on CRISPR Products
Rarely in the scientific realm does a niche technique explode into a viable market worth billions of dollars over just a handful of years. When it does, the chaos that ensues is driven by the scrambling of life science product and service providers who vie with each other to secure market share.  Discuss
Conferences
2nd Annual BioIT World Conference & Expo West
March 1-4
San Francisco, California United States
BioProcess International US West
March 9-12
Santa Clara United States
Microbiology Society Annual Conference 2020
March 30 - April 3
Edinburgh, Edinburgh, City of United Kingdom
Experimental Biology 2020
April 4
San Diego, California United States
BioProcess International Europe
April 28 - May 1
Amsterdam, Noord-Holland Netherlands
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