Spherical nucleic acids 'dramatically' expand CRISPR delivery options Researchers at Northwestern University contend that by combining nanostructures called spherical nucleic acids with CRISPR-Cas9 systems, the types of cells and tissues that the gene-editing machinery can be delivered to may be "dramatically" expanded.Read More
CRISPR edited rat embryos reveal cause of rare pediatric neurodegenerative disease Using CRISPR gene editing technology on rat embryos, University of Wisconsin-Madison researchers have revealed the mutation that is responsible for progressive gait abnormalities and other symptoms in human infants and young children with a rare neurodegenerative disease.Read More
Boosting TERRA levels damages DNA of hard-to-kill cancer cells: study Increasing levels of telomeric repeat-containing RNA (TERRA) damages the DNA of cancers with a particular form of replicative immortality and leads to cell death, according to Portuguese researchers who show that “anti-aging clocks” can be used to kill cancer cells.Read More