Genomics
A novel approach to using CRISPR: curing cystic fibrosis
Researchers are finding innovative ways to utilize CRISPR technology to permanently cure diseases, in this case, cystic fibrosis. A collaboration between the University of Trento in Italy and KU Leuven in Belgium, funded by Fondazione ricerca fibrosi cistica led to the publication of a new study in Nature Communications on August 7, 2019.  Discuss
Building proteins from scratch – how AI is helping advance synthetic biology
A new de novo designed protein – degronLOCKR, is the first completely artificial protein switch that operates within cells. LOCKR (short for Latching, Orthogonal Cage/Key pRotein) design and initial practical applications were published in Nature on July 24, 2019. Research was conducted by research teams at UW Medicine Institute for Protein Design and the University of California San Francisco.  Discuss
The CRISPR fight continues after nearly a decade
After many years of hearing about the ability to edit a genome, many of us (scientist or not) are finally getting used to the idea. However, in federal patent offices and research institutions, this topic has been and continues to be the subject of serious debate.  Discuss
Genome mining has potential uses in synthetic biology and drug discovery
Researchers discovered a cluster of genes in Pseudomonas syringae which infects plants. The results of this research were published in Science on July 19th. However, this natural product produced belongs to a special class of ribosomally synthesized and posttranslationally modified peptides.  Discuss
The European Commission pursues open science and why it’s important
Scientists believe that there is a reproducibility crisis in the scientific community where many scientists fail to reproduce experiments, according to a new report by Science | Business in July 2019. Open science is a high priority for the European Commission, with around 70% of all data generated by EU-funded programs being accessible to the public.  Discuss
New clinical trial testing effectiveness of anti-obesity drug in conjunction with genetic screening
A new phase 3 clinical trial expected to begin in late July 2019, will test an anti-obesity drug targeting people with rare genetic conditions, and will be tied to a genetic study attempting to create a more comprehensive understanding of the genes associated with obesity.  Discuss
Landmark study explores public understanding of science and trust in scientific and medical professionals
Understanding global perceptions and knowledge of science is of growing interest to the scientific community. Organizations such as 3M, with their State of Science Index Survey and the Wellcome Global Monitor (WGM), from the Wellcome Foundation and Gallup World Poll, explore attitudes towards science and medicine, and also confidence in scientists themselves.  Discuss
Leaders in science and engineering publications over the last decade: China and the US
Capturing the attention of policy makers and companies serving the academic research market the countries with the largest number of science and engineering (S&E) articles has significantly evolved between 2007 and 2017. China leads the list in 2017 followed by the US, a reverse from 2007, according to a May report from the NSF’s National Center for Science and Engineering Statistics.  Discuss
The National Institutes of Health launches the Symptom Science Center
The National Institutes of Health, National Institute of Nursing Research (NIH NINR) launched the Symptom Science Center on June 27th, 2019 at the NIH Campus in Bethesda, MD. This event, attended by over 500 individuals, marks a momentous occasion for both clinical and translational multidisciplinary research.  Discuss
A convergence of technologies, revolutionizing next-generation sequencing
A new, powerful combination of biochips and next-generation sequencing (NGS) is capable of solving unique and important biological problems, such as single-cell, rare-cell or rare-molecule analysis, which NGS can't do on its own.  Discuss
Conferences
BioProcess International Europe
July 13-17
Central European Time Zone (CET) Netherlands
2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States
Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States
General Discussion
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