Cell Biology
Microscopic defects of healthy cells affect spread of ovarian cancer cells
Biophysics researchers have applied the concept of topological defects to investigate the spread of ovarian cancer cells. Using an in vitro model, the researchers found that these defects -- or disruptions in the normal cellular layout -- can affect the rate of tumor cell invasion. Their findings were published online in APL Bioengineering on August 3. Read More
Sunlight causes DNA damage associated with melanoma
Unlike other cancers, melanoma results from a chemical reaction that damages DNA and is fueled by sunlight, according to a new study published in Science Advances on July 30. Read More
Cardiac cell protein may be key to preventing heart failure
A protein that controls calcium signaling within heart cells could help prevent chronic heart failure, according to the results of a new study published in Nature Communications on July 28. The findings point to the protein as a therapeutic target for drugs that could alleviate heart failure. Read More
Blocking some T cells may unleash full power of immune system against cancer
Researchers have identified a way to restrict regulatory T-cell activity in tumor cells, which in turn can unleash other immune cells to attack tumors in cancer patients. The research is being published in the August 3 issue of the Proceedings of the National Academy of Sciences. Read More
Cytiva, Pall to invest $1.5B in biomanufacturing over next 2 years
Cytiva and Pall, both Danaher companies, will make major investments in manufacturing capacity and services at 13 sites around the globe supporting life science customers, totaling $1.5 billion over two years. Read More
5 ways to improve the biomanufacturing workforce in regenerative medicine
A national survey of regenerative medicine biomanufacturing has revealed gaps in the training of skilled technical workers. The group behind the survey has proposed five steps to improve workforce quality and recently published its recommendations in Stem Cells Translational Medicine. Read More
Cellares, Poseida partner on cell therapy manufacturing
Poseida Therapeutics has joined Cellares' Early Access Partnership Program to accelerate cell therapy manufacturing. The collaboration is expected to provide insight into CAR T workflows as well as other technologies. Read More
Oncolytic viruses move closer to becoming effective cancer therapies
Scientists are identifying key factors that aid in the effectiveness of oncolytic viruses during the treatment of cancers, which could lead to better immunotherapies and inform clinicians which patients might benefit from the treatment. Findings from a June 22 Nature Communications article point to the clinical relevance and underlying mechanisms of a novel anticancer treatment. Read More
CAR-NK cells hold promise for solid tumors
A new cancer immunotherapy that leverages the ability of natural killer (NK) cells to discriminate between cancer and normal cells has shown promise in solid tumors. The technology incorporates the cancer-targeting ability of chimeric antigen receptors (CARs), according to data published in iScience on June 25. Read More
New in vitro models offer effective way to study respiratory viruses
A new accessible and scalable protocol for manufacturing in vitro lung cell models could have applications in the development of new therapies for respiratory viral infections and drug toxicology studies on human lungs. Details about the protocol were published in Stem Cells on June 21. Read More
Conferences
BioTech Pharma Summit
September 27-28
Porto Portugal
Infectious Diseases (ID) Week 2021
September 29 - October 3
San Diego, California United States
Imaging Mass Spectrometry Society (IMSS) 3 in 2021
October 3-6
Colorado Springs, Colorado United States
Cell & Gene Meeting on the Mesa
October 10-14
Carlsbad, California United States
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter