AI provides evidence that gene length explains age-related molecular changes Artificial intelligence (AI) has helped Northwestern University researchers find evidence that the length of genes explains most of the molecular-level changes that occur during aging, which they contend could lead to therapeutics that slow or even reverse the process.Read More
Functional genomics reveals gateway to intracellular targets for large molecules Complementary genome-scale, chemical-genetic approaches have revealed a cellular gateway that could allow large molecules to enter cells, providing new opportunities to develop drugs for intracellular targets, according to University of California San Francisco (UCSF) researchers.Read More
Senescent neuron discovery in brains opens path for Alzheimer's drug development Scientists at the Salk Institute for Biological Studies have found that neurons from people with Alzheimer's disease show deterioration and undergo a late-life stress process called cellular senescence, while senescent cells could be a way to slow neuroinflammation and neurodegeneration.Read More
New computational method maps architecture of human tissues in unprecedented detail Weill Cornell Medicine researchers have developed a new computational method to map the architecture of human tissues in unprecedented detail, with the potential to accelerate studies on organ-scale cellular interactions and enable powerful new diagnostic strategies for an array of diseases.Read More