Rare cancer study identifies patients at high risk of metastasis
A large genomic study of a rare cancer called metastatic pheochromocytoma identified patients at high risk of metastasis, as well as those most likely to respond to immunotherapy. The results, published in Nature Communications on February 28, may allow closer following up of patients with poor prognoses, and facilitate more personalized treatments. Read More
Video from AACC: Lab Ordering Cloud software
Mehdi Maghsoodnia, CEO of 1health, spoke to ScienceBoard.net's sister site LabPulse.com about the market needs for the firm’s Lab Ordering Cloud, as well as diagnostic industry trends. Read More
Market access and patient education take center stage at Meeting on the Med
Companies and patient groups tackled reimbursement hurdles and access challenges in a discussion at the Cell & Gene Meeting on the Med last week in Barcelona, Spain. Titans of the pharmaceutical industry took the stage to discuss important issues facing the growing segment, including patient education, reimbursement, and clinical trials. Read More
Applied DNA and EvviVax publish data for potential cancer immunotherapy
Applied DNA Sciences and EvviVax have published a manuscript detailing a preclinical study showing that LinearDNA vaccines used for cancer immunotherapy produced a strong immune and specific antitumoral response in preclinical mouse models. The study investigated the use of the LinearDNA platform to produce DNA vaccines targeting either tumor-associated antigens (TAAs) or tumor-specific antigens (TSAs, or tumor neoantigens). Read More
Colonic gene mapping provides insights into intestinal diseases
Researchers have used spatial transcriptomics to uncover an unprecedented view of the molecular regionalization of the murine colon. This research, published in Nature Communications on February 11, provides novel insights into inflammatory bowel disease. Read More
EpiCypher, New England Biolabs codevelop Cut&Run library prep kit
EpiCypher has entered into a partnership with New England Biolabs (NEB) to codevelop a first-in-class library prep kit specifically optimized for best performance with EpiCypher’s CUTANA Cut&Run epigenomic assays. Read More
CHOP uses AI to find genetic causes of mental health disorders
Minority populations have been historically underrepresented in existing studies addressing how genetic variations may contribute to a variety of disorders. A new study from researchers at the Children's Hospital of Philadelphia (CHOP) addresses this lack of representation, showing that a deep learning model has promising accuracy when helping to diagnose a variety of common mental health disorders in African American patients. Read More
CAR T-cell therapy collaborations expand cancer treatment options
Considering the broad range of the causes of cancer and the heavy impact on patients, advanced and innovative treatments are essential to fighting it. One technology being explored for this purpose is CAR T-cell therapy, because it trains the body's immune system to specifically target cancerous cells, according to Cell and Gene Therapy Business Outlook, a sister publication of ScienceBoard. Some healthcare institutions are collaborating with companies to develop such technologies, including Celularity, Lonza, and the Memorial Sloan Kettering Cancer Center. Read More
Rare disease treatments continue to advance alongside gene therapies
Rare diseases represent an underserved and frequently overlooked area in healthcare. As a result, funding for research in these diseases is often limited. However, many of these diseases are fatal or highly impair a patient's quality of life. According to a recent report from Cell and Gene Therapy Business Outlook, a sister publication of ScienceBoard, some institutions are focusing their efforts in the area of rare diseases. Read More
Roche automates next-gen sequencing sample prep
Roche announced the launch of the Avenio Edge System, a core component of Roche's strategy to advance sequencing technologies. The system is built on Roche's foundational capabilities to deliver a fully automated, integrated sequencing solution. Read More
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