FDA approves cell therapy treatment for transplantation in blood cancer patients
The U.S. Food and Drug Administration (FDA) on Monday approved the product Omisirge, a cell therapy treatment, for transplantation in blood cancer patients. The phase III trial results, published October 21, 2021, in the journal Blood, found the efficacy of Omisirge transplantation superior to standard umbilical cord blood transplantation. Read More
NCI study outlines challenges, opportunities in achieving Cancer Moonshot goals
Researchers at NIH’s National Cancer Institute (NCI) have found that accelerated progress is needed to achieve President Joe Biden’s Cancer Moonshot goal of reducing cancer death rates in the U.S. Read More
Researchers find new target for drug-resistant ovarian cancer
Researchers working in a preclinical study have verified a new target for recurrent drug-resistant ovarian cancer and provided data to support a treatment approach now in clinical trials. The findings were presented on Sunday, during the American Association for Cancer Research (AACR) 2023 annual meeting. Read More
Immunotherapy improves lung cancer outcomes
In a clinical trial, a regimen of pre-surgical immunotherapy and chemotherapy followed by post-surgical immunotherapy significantly improved outcomes compared to chemotherapy alone for patients with operable non-small cell lung cancer (NSCLC). Read More
Plasmid DNA vaccine protects mice from COVID-19 by triggering T-cell response
A plasmid DNA vaccine designed to trigger a T-cell response has protected most mice from a lethal dose of SARS-CoV-2, delivering preliminary evidence that the candidate may provide broader, more durable responses than existing COVID-19 shots. Read More
RNA sequencing database reveals how mutations accrue in different tissues as humans age
The application of bulk RNA sequencing to samples from almost 1,000 donors has created an atlas of the mutations that accrue in different tissues as people age. Read More
Testing vaccine candidates with lab-grown organoids
Researchers have developed a new testing platform that encapsulates B cells -- important immune system components -- into miniature lab-grown organoids. The results, published Wednesday in ACS Central Science, may hasten vaccine screening and significantly reduce the number of experimental animals used in the process, the researchers said. Read More
Hallmark Parkinson’s disease protein may aid early detection
A technique that identifies the build-up of abnormal protein deposits linked to Parkinson’s disease could aid in early diagnosis. Read More
Experts urge hospitals to establish C. difficile prevention programs in updated guidance
Five medical organizations have urged hospitals to establish programs to prevent Clostridioides difficile infections in updated guidance on the public health threat. Read More
Mayo Clinic, Alpenglow Biosciences collaborate to advance pathology, drug development through 3D spatial biology
Seattle-based Alpenglow Biosciences on Wednesday announced a collaboration with Mayo Clinic to adopt the firm’s 3D spatial biology platform with the aim of accelerating drug development and advancing clinical diagnostics. Read More
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