Cancer & Disease Research
Enrichment NGS emerges as surveillance tool for coronavirus
As the coronavirus continues to grow as a global health concern, researchers urgently seek efficient methods to predict and mitigate emerging coronavirus strains. An international team of researchers believes that targeted next-generation sequencing (NGS) may be a valuable tool for monitoring both current and future outbreaks of coronavirus originated from bats. Read More
Nanoparticles eat cardiovascular plaques from the inside out
Scientists have engineered a nanoparticle that eats plaques associated with cardiovascular disease -- from the inside out. This Trojan horse technology could offer a new therapeutic option for the treatment of atherosclerosis, according to a study published in Nature Nanotechnology on January 27. Read More
Stem cell findings help researchers learn about early-onset Parkinson's
New research utilizing stem cells indicates that the metabolic processes that lead to young-onset Parkinson's disease could begin years before symptoms of the disease emerge. But the findings also point to a potential drug candidate that could be used to treat the condition, according to a study published January 27 in Nature Medicine. Read More
Microscopy with fluorescent tags gives high-def view of diabetes-related proteins
Leveraging the power of new imaging techniques, scientists are using unique fluorescent tags in combination with superresolution microscopy to gain novel insights into a receptor that plays a key role in controlling blood sugar levels. These insights will open the door to improved treatment options for type 2 diabetes. Read More
New study offers hope for short-circuiting KRAS-driven lung cancers
The protein kinase p38α has been identified as a key element supporting KRAS-driven lung cancers, so inhibiting the protein has potential as a target for the treatment of certain lung cancers. An international group of researchers used genetic mouse models with the KRAS mutation to observe how p38α inhibition reduces tumor growth. The work was published in the Proceedings of the National Academy of Sciences on January 22. Read More
Small-molecule chaperones may reverse Alzheimer's symptoms in mice
A novel treatment for Alzheimer's disease involving the administration of pharmacological chaperones that prevent amyloid beta and tau tangles from forming in the brain may be possible, according to a new study published online on January 22 in Molecular Neurodegeneration. Read More
Yeast metabolism may offer lessons on starving cancer cells
Scientists may have found a new way to starve cancer cells by learning from growth regulation mechanisms employed by yeast. They found that the same metabolic mechanism used by yeast to respond to nutrient shortages is also employed by mammalian cells -- a finding that could lead to new cancer therapies, according to a new study published in Nature Metabolism on January 20. Read More
Scientists learn how lactate contributes to cancer formation
Previously considered a waste product of metabolism, lactate may play a crucial role in cancer growth, according to a study published in Frontiers in Oncology on January 14. Researchers from the University of Colorado Anschutz Medical Campus explored how lactate affects transcription of oncogenes in breast cancer cells. Read More
Scientists in the Lab: Featuring Lisa Mustachio
Continuing our feature series this January, ScienceBoard is happy to highlight the work of laboratory scientists, including Lisa Maria Mustachio, PhD, a postdoctoral fellow at MD Anderson Cancer Center. Read More
Dietary probiotics show potential to reverse Parkinson's symptoms
Roundworms that were fed a commercially available dietary probiotic showed less buildup of proteins that form during the progression of Parkinson's disease in a new study, published in Cell Reports on January 14. The finding provides further evidence of a link between the gut microbiome and brain function. Read More
Conferences
BioTech Pharma Summit
September 27-28
Porto Portugal
Infectious Diseases (ID) Week 2021
September 29 - October 3
San Diego, California United States
Imaging Mass Spectrometry Society (IMSS) 3 in 2021
October 3-6
Colorado Springs, Colorado United States
Cell & Gene Meeting on the Mesa
October 10-14
Carlsbad, California United States
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