Transomic analysis reveals the network regulated by an enzyme implicated in diabetes
Light-sensitive molecules have enabled researchers to map the genes, enzymes, and metabolites that are implicated in diabetes and metabolic disorders. Read More
Meta-analysis reveals roadmap for effective use of convalescent plasma in pandemics
A meta-analysis has linked the administration of convalescent plasma to a reduced rate of hospitalization for COVID-19, suggesting that the readily accessible treatment could play an important role in a future viral pandemic. Read More
Toxic protein linked to both muscular dystrophy and arhinia
National Institutes of Health (NIH) researchers and collaborators have found that DUX4, a toxic protein made by the body, may be responsible for two very different rare genetic disorders. The study, published on Friday in Science Advances, may eventually lead to therapies that can help people with a type of muscular dystrophy, as well as those with a facial malformation called congenital arhinia. Read More
COVID-19 infection provides natural immunity, at least for a while: Lancet study
A systematic review and meta-analysis found that individuals previously infected with COVID-19 have an 88% lower risk of hospitalization or death for at least the following 10 months compared with those not previously infected. Read More
Meta-analysis reveals which antibody appears best at preventing RSV infection
A meta-analysis has found an investigational antibody is as effective at preventing respiratory syncytial virus (RSV) infection and associated negative health outcomes as the incumbent product. Read More
Adaptive Biotechnologies Q4 revenues rise 46% on NGS test volumes
Adaptive Biotechnologies on Tuesday reported fourth-quarter revenue of $55.2 million, up 46% compared with $37.9 million in Q4 2021. Read More
Multidrug-resistant bacteria cooperate to reduce the impact of antibiotics: study
Two of the most dangerous multidrug-resistant pathogens work together to nullify antibiotics, suggesting physicians need to determine if both bacteria are present before selecting a treatment regimen. Read More
Paxlovid effective against Omicron subvariants in study
Colorado researchers investigated the effectiveness of the drug nirmatrelvir-ritonavir, also known as Paxlovid, in non-hospitalized patients during a time period in which Omicron subvariants BA.4 and BA.5 were prevalent. Read More
CAR-T cell therapies eliminate residual, drug-resistant lung cancer cells in preclinical tests
Targeting a cell surface protein could eliminate the lung cancer cells that survive treatment with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs), according to a paper published on Monday in Cancer Cell. Read More
Ingestible ‘smart pill’ may pinpoint GI disorders
Researchers have developed an ingestible pill that utilizes magnetic fields to precisely track its movement through the gastrointestinal tract. The findings, published February 13 in a Nature Electronics study, may facilitate the diagnosis and treatment of gastrointestinal (GI) disorders, according to the authors. Read More
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