Cancer & Disease Research
Communication of cancer cells analyzed with organoids and novel cytometry
A new technique using organoids, self-organizing 3D tissue models, can decipher how individual cancer cells communicate with each other and the unique signals they create. This research, published in Nature Methods on February 17, could be used to help develop personalized cancer treatments in the future.  Discuss
Atomic structures revealed by cryo-EM may lead to new antiviral drugs
Using cryo-electron microscopy (cryo-EM), researchers found unique structures of paramyxoviruses that can lead to a better understanding of viral replication, which in turn can be leveraged to develop improved antiviral drugs. The details were published in the Proceedings of the National Academy of Sciences on February 17.  Discuss
Genetically engineered probiotics successfully deliver immunotherapies
A new technology enables genetically engineered probiotic bacteria to be used as an efficacious, stable, and safe platform to deliver immunotherapies directly into a variety of tumors in just a single dose. The research was published online on February 12 in Science Translational Medicine.  Discuss
T cells work as a team to fight infection
Immune cells may be better at sensing each other than previously thought, according to a new study published in Immunity on February 11. Researchers from Germany, the Netherlands, and the U.K. revealed a mechanism T cells use to work as a team and mutually determine how to fight infections.  Discuss
CRISPR proteins developed for use in molecular diagnostics
New CRISPR technology is being developed as a molecular diagnostic tool with the capability of detecting unique disease biomarkers. Eventually, these at-home tests will allow patients to conduct at-home diagnostic tests quickly.  Discuss
3D model of human intestines helps simulate leaky gut condition
Researchers are using 3D models of human intestines to simulate leaky gut conditions -- in which microbes and molecules seep out of the intestines, eliciting an immune response. The research, published in Life Science Alliance on February 10, will help identify biomarkers for leaky gut for improved diagnostics and treatment development.  Discuss
Genomics sheds light on the life history of cancers
As part of a special collection of papers on pan-cancer analysis of whole genomes published online by Nature on February 6, an international group of scientists analyzed over 2,500 unique cancer genomes to shed light on the life history of cancer mutations and how cancer tumors evolve -- even before they are diagnosed.  Discuss
New fluorescence technique builds more vivid views
A novel imaging technique improves processing time of hyperspectral fluorescence imaging and allows scientists to peer more deeply and clearly into living organisms. Researchers from the University of Southern California Michelson Center for Convergent Bioscience have been developing the technology for years and have published their findings in Nature Communications on February 5.  Discuss
Math models improve the effectiveness of immunotherapy
Scientists working at the intersection of math and medicine propose new strategies based on mathematical modeling and known molecular mechanisms to improve the efficacy of lifesaving immunotherapies for cancerous tumors. The work was published on February 3 in the Proceedings of the National Academy of Sciences.  Discuss
Chinese researchers mobilize to classify 2019-nCoV
In response to a recent outbreak of the novel coronavirus (2019-CoV), scientists in China have uncovered genetic similarities with severe acute respiratory syndrome (SARS) coronaviruses by analyzing patient samples from the source of the outbreak. Their findings provide crucial evidence that will aid in the classification and identification of 2019-CoV, according to a new report published in Nature on February 3.  Discuss
Conferences
BioProcess International Europe
July 13-17
Central European Time Zone (CET) Netherlands
2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States
Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States
General Discussion
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