Bioimaging & Microscopy
Small-molecule chaperones may reverse Alzheimer's symptoms in mice
A novel treatment for Alzheimer's disease involving the administration of pharmacological chaperones that prevent amyloid beta and tau tangles from forming in the brain may be possible, according to a new study published online on January 22 in Molecular Neurodegeneration.  Discuss
Correlative microscopy provides view of subcellular components
As technology improves and knowledge of molecular biology increases, there is a need to view and analyze the complex organization of cells. That's become possible thanks to a new methodology based on correlative microscopy, which uses a combination of fluorescence and electron microscopy to seamlessly zoom in and out of a sample. The protocol was described in Science on January 17.  Discuss
Dietary probiotics show potential to reverse Parkinson's symptoms
Roundworms that were fed a commercially available dietary probiotic showed less buildup of proteins that form during the progression of Parkinson's disease in a new study, published in Cell Reports on January 14. The finding provides further evidence of a link between the gut microbiome and brain function.  Discuss
Scientists in the Lab: Featuring Nicole Lindor
ScienceBoard is happy to continue to feature scientists in the lab this month. The next scientist we are featuring is Nicole Lindor, a doctoral candidate at North Carolina State University.  Discuss
Control of molecular 'doormen' in fat cells offers potential new obesity treatment
New treatment options for obesity could emerge from a study published in Nature Communications on January 10. Researchers from Yale University School of Medicine utilized cellular and molecular approaches to identify pathways to restore the healthy balance of fat cells.  Discuss
Improving melanoma immunotherapies by regulating Treg proliferation
A new pathway to regulating anti-tumor immunity and increasing the effectiveness of PD-1 therapies was identified by scientists at Sanford Burnham Prebys Medical Discovery Institute. The results were published in Nature Communications on January 7.  Discuss
Researchers elucidate mechanotransduction pathways of transmembrane proteins
Researchers from Imperial College London, Queen Mary University of London, and Tampere University in Finland present new mechanistic pathways for transmembrane proteins with implications in drug discovery and development. The results of the study were published in Nature Materials on January 6.  Discuss
Algorithm provides new insight into hierarchical DNA structures that influence disease
Researchers develop an algorithm that locates specific topologically associating domains (TADs) which are implicated in disease development, including cancer. The technology, called OnTAD, can examine internal architectures of TADs, which are important in elucidating their biological functions. The work was published in Genome Biology on December 18.  Discuss
Ghost imaging speeds up nanoscopy techniques
Researchers from the Chinese Academy of Sciences describe a new unconventional super-resolution imaging, or nanoscopy, technique that processes nanometer resolution with fewer frames than traditional methods. This combinatorial process involves several processes to achieve super-resolution, overcome the diffraction of light, and capture changing dynamics with a faster technique.  Discuss
Scientists develop a first-of-its-kind in vitro 3D neural tissue model
Researchers from the University of Illinois at Urbana-Champaign have successfully used stem cells to engineer nerve tissues as 3D models of neural networks to study brain function. The work was published in the December 3 edition of the Proceedings of the National Academy of Sciences.  Discuss
Conferences
2nd Annual Cell Therapy Bioprocessing Conference
June 25-26
Boston, Massachusetts United States
BioProcess International Europe
July 13-16
Amsterdam, Noord-Holland Netherlands
Bioprocess International West
August 10-13
Santa Clara, California United States
BioProcess International
September 21-24
Boston, Massachusetts United States
General Discussion
Topic Replies / Views Last Update
Open science for the modern scientific community
by LMoraes
3 / 53 More than 3 days ago
by The Mets
https://academic.oup.com/ve/pages/coronavirus-evolution
by Michael
0 / 14 More than 3 days ago
by Michael
PopSci Hails Impossible Burger 2.0 as Most Important Engineering Innovation in 2019
by Mahesh Gupta
0 / 8 More than 3 days ago
by Mahesh Gupta
Engineered Bacteria Produces BeeFree Honey
by Mahesh Gupta
0 / 11 More than 3 days ago
by Mahesh Gupta
Consumers' Preference to Buy Unlabeled Produce Increases after Exposure to GMO-labeled Pro
by Mahesh Gupta
0 / 14 More than 3 days ago
by Mahesh Gupta
To see more posts from our community or to share a post of your own, go to our community's forum page.
Conferences
2nd Annual Cell Therapy Bioprocessing Conference
June 25-26
Boston, Massachusetts United States
BioProcess International Europe
July 13-16
Amsterdam, Noord-Holland Netherlands
Bioprocess International West
August 10-13
Santa Clara, California United States
BioProcess International
September 21-24
Boston, Massachusetts United States
Connect
Science Advisory Board on LinkedIn
Science Advisory Board on Facebook
Science Advisory Board on Twitter