Analytical Chemistry
Scientists alter cell function with genetic engineering, polymer science
A new method called genetically targeted chemical assembly (GTCA) has demonstrated the ability to build artificial structures within the body to carry out unique functions. The research, presented in the latest edition of Science, provides compelling evidence for GTCA's ability to modify cell function with bioengineering tools.  Discuss
Could more sugar-based drugs be on the way?
Researchers from Denmark have developed a new technique to characterize complex sugar molecules in exquisite detail never before achieved, according to a report published on March 20 in Nature Communications. They hope to leverage the new structural information for the development of therapies.  Discuss
New lung cancer biomarker could significantly improve patient outcomes
A new protein has been identified on tumor-derived extracellular vesicles that indicates if a lung tumor is likely to metastasize, according to research published in Science Advances on March 11. A minimally invasive biomarker test to catch cancer early could significantly improve patient outcomes.  Discuss
Low Pittcon attendance doesn't deter from quality program
Attendance was down at last week's Pittcon conference in Chicago, but organizers of the meeting for laboratory scientists may actually have been lucky that their show took place at all, given the wipeout of science and health meetings in March due to the coronavirus outbreak.  Discuss
Scientists identify chaperones as potential therapies for Parkinson's disease
Researchers from the University of Basel have identified the malfunctional relationship and master regulatory mechanisms between chaperone proteins and α-Synuclein occurring in Parkinson's disease. The findings were published in Nature on December 4.  Discuss
A discovery of fungi – helping researchers identify new drugs
To address the need to identify new therapeutic targets, researchers at the Hubrecht Institute turned to fungi. The researchers tested secondary metabolites from over 10,000 fungi species and identified 34 biological active compounds with the potential to move to the next step of therapeutic drug development. The research was published in Scientific Reports on November 26.  Discuss
Novel strategy for studying mitoribosomal and mitochondrial impact on disease
Researchers from the Karolinska Institutet in Sweden have developed a new experimental tool for studying mitochondrial protein synthesis in vivo. This research is presented in the October 5 issue of Cell Reports.  Discuss
Biologically active molecules in coal are found to have antiviral properties against tick-borne encephalitis
Scientists from Russia demonstrated in a Scientific Reports article published on August 19, that biologically active molecular components of substances extracted from coal, humic substances, have antiviral properties. A novel approach to identify these molecules determined that these molecules inhibit the reproduction of tick-borne encephalitis virus (TBEV), which causes clinically relevant human viral infectious disease.  Discuss
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Conferences
2nd Annual Cell Therapy Bioprocessing Conference
June 25-26
Boston, Massachusetts United States
BioProcess International Europe
July 13-16
Amsterdam, Noord-Holland Netherlands
Bioprocess International West
August 10-13
Santa Clara, California United States
BioProcess International
September 21-24
Boston, Massachusetts United States
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