Analytical Chemistry
SARS-CoV-2 rewires host proteins to promote infection
To successfully infect human cells, SARS-CoV-2 may hijack host proteins in target cells to promote its own replication. Researchers may be able to leverage this information to identify and recommend drugs, according to a June 29 Cell article.  Discuss
Some viruses may steal host genes to form beneficial hybrid proteins
Certain types of RNA viruses may be capable of using host RNA to expand their own genetic repertoire, according to a new study published in Cell on June 18. This mechanism may enable viruses to overcome the limitations of small genomes and more effectively infect host cells.  Discuss
Manufacturers adapt technologies for hand sanitizers during COVID-19
Changes to manufacturing processes have emerged to meet the demand of certain products during the COVID-19 pandemic, including hand sanitizer. The chemical composition of hand sanitizer is carefully regulated, and analytical techniques are now being repurposed to assist in rapid production efforts.  Discuss
Proteomics provides insights into SARS-CoV-2 infection, potential therapies
Scientists tested a series of compounds for blocking the replication of SARS-CoV-2 using a novel proteomics approach. The method, which helped identify small-molecule drugs that may be effective at treating COVID-19 patients, was published in Nature on May 14.  Discuss
New STM technique could lead to purer pharmaceuticals
A research project led by chemists at the University of Warwick has revealed how ultrahigh-resolution scanning tunneling microscopy (STM) can be used to determine precise molecular interactions, which could be particularly useful for the production of raw materials. The report was published in Nature Communications on April 30.  Discuss
Scientists alter cell function with genetic engineering, polymer science
A new method called genetically targeted chemical assembly (GTCA) has demonstrated the ability to build artificial structures within the body to carry out unique functions. The research, presented in the latest edition of Science, provides compelling evidence for GTCA's ability to modify cell function with bioengineering tools.  Discuss
Could more sugar-based drugs be on the way?
Researchers from Denmark have developed a new technique to characterize complex sugar molecules in exquisite detail never before achieved, according to a report published on March 20 in Nature Communications. They hope to leverage the new structural information for the development of therapies.  Discuss
New lung cancer biomarker could significantly improve patient outcomes
A new protein has been identified on tumor-derived extracellular vesicles that indicates if a lung tumor is likely to metastasize, according to research published in Science Advances on March 11. A minimally invasive biomarker test to catch cancer early could significantly improve patient outcomes.  Discuss
Low Pittcon attendance doesn't deter from quality program
Attendance was down at last week's Pittcon conference in Chicago, but organizers of the meeting for laboratory scientists may actually have been lucky that their show took place at all, given the wipeout of science and health meetings in March due to the coronavirus outbreak.  Discuss
Scientists identify chaperones as potential therapies for Parkinson's disease
Researchers from the University of Basel have identified the malfunctional relationship and master regulatory mechanisms between chaperone proteins and α-Synuclein occurring in Parkinson's disease. The findings were published in Nature on December 4.  Discuss
Conferences
BioProcess International Europe
July 13-17
Central European Time Zone (CET) Netherlands
2020 ACCP Annual Meeting
September 20-22
Bethesda, Maryland United States
Bioprocess International West
September 21-24
Eastern Standard Time Zone (EST) United States
General Discussion
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