Analytical Chemistry
Could more sugar-based drugs be on the way?
Researchers from Denmark have developed a new technique to characterize complex sugar molecules in exquisite detail never before achieved, according to a report published on March 20 in Nature Communications. They hope to leverage the new structural information for the development of therapies.  Discuss
Chemists develop method to identify protein neighbors
A new technology called µMap uses photocatalysts, molecules that spur a chemical reaction when activated by light, to identify spatial relationships of cell surface proteins. The results are described by scientists from Princeton University and Merck in the March 6 edition of Science.  Discuss
Microscale flow chemistry uses 'switchable solvents' to improve extraction
New green technology enables accelerated screening and retrieval of "switchable" solvents for chemical and pharmaceutical applications. Utilizing microfluidic strategies, researchers developed an in situ approach to study gas-liquid processes in a time- and material-efficient manner. The work was published online in ACS Sustainable Chemistry and Engineering on February 6.  Discuss
Bacterial evolution reveals method to fight antibacterial resistance
Different types of bacteria have evolved to develop unique mechanisms for achieving the same antibacterial function -- a finding that could lead to new ways to combat antibacterial resistance, according to scientists from Trinity College Dublin. They tested their findings using methicillin-resistant Staphylococcus aureus in a study that was published in Nature Communications on January 9.  Discuss
New chemistry technique builds more precise nanoparticles
New research published in Nature Communications on November 27th demonstrates a new chemical technique that provides researchers enhanced control over the size and shape of nanoparticles used in drug delivery systems.  Discuss
New bio-imaging techniques help scientists understand the early stages of Parkinson's disease
Scientists observed, for the first time ever, how variants of Parkinson's disease-associated protein alpha-synuclein change over time and identify the initial stages of protein aggregates. A new study published in Nature Communications on October 10 helps to clarify the why treatment challenges associated with Parkinson's disease (PD), when does it begin.  Discuss
Chemists develop new technique to build super-active catalysts
New highly desirable catalysts, made mostly of precious metals, have 24 different faces that present atoms at the surface in ways that make them more catalytically active than current commercially available products.  Discuss
Breakthrough electrochemical technique may bring cost savings to drug companies
Researchers have developed a simple new method for the creation of hindered ether compounds, which are often important components of many drugs and commercial products. Hindered ethers have been traditionally difficult to manufacture, but scientists at Scripps Research have published a new electrochemistry technique in Nature on September 9, which allows these compounds to be produced faster and more efficiently.  Discuss
Fluorescent molecular probe used to detect temperature inside individual cells
Modified biocompatible molecular rotor, termed boron dipyrromethene (BODIPY), has been shown to detect temperatures inside single cells. Researchers at Rice University led by chemist Angel Mart√≠ published the technique in the Journal of Physical Chemistry B.  Discuss
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