Member SpotlightsSelf-Maintenance of Gene and Occurrence of Genetic Diseases Dr. Xuefeng Pan A Science Advisory Board Member Since 2010  Dr. Xuefeng Pan is Principal Investigator of the Genomic Instability Group and Chair of Molecular Biology at the Beijing Institute of Technology. Educational Background: I received a Bachelors of Science in Biochemistry and Microbiology from Hebei University in China. After graduation I was awarded an assistant professorship in Public Health in Epidemic and Hygiene Station of Langfang City and Wenan School of Public Health. One year later, I completed my Master’s at the Graduate School of the Chinese Academy of Sciences and the University of Science and Technology of China in Beijing. In 1997 I was awarded my Ph.D in Biochemistry from Institute of Microbiology at The Chinese Academy of Sciences. After receiving my doctoral degree, I decided to take a position as a MRC Postdoctoral Research Fellow at the University of Edinburgh in the UK. Professional Background: I am an Associate Professor of Molecular Biology and Medicine, as well as Principal Investigator of the Genomic Instability Group in the Department of Biotechnology of the School of Life Science & Technology in China. I am also Adjunct Professor of Molecular Medicine of HSC Hebei University. Academic and Professional Interests: My research interests include nucleic acid and protein manipulations but most importantly, I enjoy researching DNA damage and repair mechanisms related human diseases. I have authored numerous articles and books related to this field of biology. Awards and Professional Memberships: Excellent Course Award of Beijing Institute of Technology ( Elaborate Course Award) 2008 Marquis Who’s Who in Science and Engineering 10th Edition 2007 Distinguished Academic Staff of Beijing Institute of Technology 2006 Advisory Directorship of Beijing Biosense Bioengineering Co LtD National Professional Certificate for University Teacher Qualification of China National 1st Class Certificate for Higher Education Qualification (Issued by National Committee for Higher Education Cooperation) Awards for Excellent thesis for Master Degree (By Chinese Academy of Sciences) Council Member of Hebei Society for Botany (Langfang Chapter) Member of IUPAC Creating Member of Chinese Society of Biotechnology Member of Chinese Society for Microbiology Member of Chinese Genetics Society Other Interests: In my spare time I enjoy hiking and traveling. My family has moved to Australia so I shuttle between Beijing and Sydney. Seeing world and visiting new countries is so exciting. Motivations: I entered the field of biology because I have always wanted to understand why living things are able to sustain life and the mechanisms that keep them alive. I have also always been interested about the relationship between what living organisms can do to and for us and vice versa. It intrigues me why human beings and others are susceptible to illness sometimes and other times they are not. Impacting how medicine currently treats aliments and how we can improve these treatments in the future are all the types of questions that intrigued me from a young age. I must admit that I was greatly influenced by my father, who is also a doctor. I knew from a young age that I would be involved in biology. Publications: Books: [1] Pan, Xuefeng (2009) Self-Maintenance of Gene and Occurrence of Genetic Diseases. (Second Edition) Science Press, [2] Pan, Xuefeng (2008) 21st Century Higher Institutes Course Series: Modern Molecular Biology . pp431. Science Press, Beijing [3] Pan, Xuefeng (2007) My Very Own Medicine -Key notes for modern public health. (pp236) Chemical Industry Press of China,Beijing. [4] Pan, Xuefeng (2004) Self-Maintenance of Gene and Occurrence of Genetic Diseases. (Pp1~403) Science Press, Beijing. (Recommended as ‘Excellent Life Science books in 2005’, by Shanghai Institutes for Life Sciences, Chinese Academy of Sciences) [5]Pan, Xuefeng (2006) Chinese-English Molecular Biological Experimental Cousre, internal publication in Beijing Institute of Technology, is used by the University Students. Articles and Journals: 1] Pan, Xuefeng , Yunmen Liu, Yuanhong Liao (2008) Transcription mediated AAT ATT Repeats Instability and its control by IS1E transposition in E.coli Nucleic Acids Res. [2] J Long P chang and Pan Xuefeng (2009) Propagation of AGG repeats in Escherichia coli relies on both repeats orientation and the RecBCD pathway of Homologous Recombination. Mol Genet Genomics (SCI) (Submitted) [3] Qiu JF and Pan Xuefeng (2009) Tracing the distribution of the functional recombination repair protein RecR in vivo. Progress in Natural Science (SCI) (In press) [4] Ding YF and Pan Xuefeng （2009）Current Research on the Molecular Mechanism of Trinucleotide Repeats (GAA·TTC)n Expansion. International J Genetics. (In Press) [5] Pan, Xuefeng , Yunfeng Ding and Lingfeng Shi (2009) The roles of sbcCD and rne in GAA·TTC Repeats Transcription in Escherichia coli. DNA Repair. (SCI) (In Revision) [6] Shao chun Li…Xuefeng Pan （2008）Progress in Microsatellite DNA Stability and Human Diseases Investigation. Heredities(Beijing) (in revision) [7] Qiu, Jiefang and Pan, Xuefeng (2008) The Linkage of DNA Replication, Repair and Recombination in Escherichia coli. Progress in Biochemistry and Biophysics2008,35(7):751-756 (SCI) [8]. Pan, Xuefeng (2007) The medicine for Everybody-Key notes for modern public health. Chemical Industry Press, Beijing. [9]. Pan, Xuefeng (2006) The Cloning and Propagation of an Inverted Repeat DNA in M13 Bacteriophage in Escherichia coli. Microbiol. Res. (in press) (PubMed,Sci,EI). [10]. Pan, Xuefeng (2006) Mechanism of Trinucleotide Repeats Instabilities: The Necessities of Repeat non-B Secondary Structure Formation and the Roles of Cellular Trans-acting Factors J.Genet&Genomics 33 (1);1-11 (SCI/PubMed,CA,BA etc). [11]. Pan, Xuefeng, (2006) Effects of degU32(Hy), degQa and degR Pleiotropic Regulatory Genes on the Growth and Protease Fermentation in Bacillus Subtilis Ki-2-132. J.Genet&Genomics 33(4)373-380 (SCI/PubMed,CA,BA etc). [12].Pan, Xuefeng (2004) Self-Maintenance of Gene and Occurrence of Genetic Diseases. (pp1~403) Science Press, Beijing. [13]. Pan, Xuefeng (2004) Determination of the reopening temperature of a DNA hairpin structure in vitro. Eur.J.Biochem 271(18):3665-3670. (PubMed/SCI) [14].Pan, Xuefeng (2004)Two-triplet CGA repeats impede DNA replication in bacteriophage M13. Microbiol. Res. 159(2):97-103(PubMed,Sci,EI) [15].Chen H. Pan, Xuefeng et al., (2001) Site-directed Mutagenesis at disulfide bond Cys206-Cys210 of prochymosin(chymosin).Chin. J. Biotechnol. 17(1):7-10.(PubMed) [16].Pan, Xuefeng and Leach, D.R.F(2000) The roles of mutS, sbcCD and recA in the propagation TGG repeats in E.coli. Nucleic Acids Res. 28(16): 3178-3184. (PubMed/SCI) [17].Pan, Xuefeng, Zhang, Y., and Tang, M.H.,(1997) The genetic effects of degUS gene in B.subtilis Ki-2-132. Acta Genetica Sinica, 24(3);282-288(PubMed:9361457). [18].Pan, Xuefeng, Zhang, Y., and Tang, M.H.,(1997) Study on the recombination assay by protoplast fusion with two bacillus strains. Chin. J. of App.& enviro. Biology. 3(1):63-66. [19].Pan, Xuefeng, Zhang, Y., andTang, M.H.,(1996)Study on highly expressive genetic engineering systems in B.subtilis Ki-2-132. High Technology Lett. 6(6):46-51(EI Journal, Chemical Abstracts:Fermentation and Bioindustry Chemistry. 125(19):958). [20]. Pan, Xuefeng, Zhang, Y., and Tang, M.H.,(1995) The high secretary phenotype caused by D-cycloserine resistent mutation in B.subtilis Ki-2-132. Proceedings of China International Symposium on Biotechnology and Pharmaceutical Industries. 67-69( Chinese Biochemical and Molecular Biology Society eds.) Shanghai, China. [21]. Pan, Xuefeng, and Tang, M.H.,(1994) Trends in Bacillus Genetics. In Rev on Microbial Genetics(Sheng, Z.J., and Chen, Y.Q. eds) 91-110. Fudan University Press. Shanghai, China. [22].Pan, Xuefeng, Huang,F., and Tang, M.H.,(1993) The studies on expression of alkaline protease in B.subtilis Ki-2-132. Ann. Rep. of Institute of Genetics of Chinese Academy of Sciences. Vol13. Beijing Polytechnic University Press, Beijng, China. [23].Pan, Xuefeng, Hu,L., and Tang, M.H.,(1992) The effects of degR,hpr,degUS32(Hy), degQ36, degQ on the degradative protease production in B.subtilis Ki-2-132. Ann. Rep. of Institute of Genetics of Chinese Academy of Sciences.Vol12:11-12. Beijing Polytechnic University Press, Beijng, China. [24].Pan, Xuefeng, and Tang, M.H.,(1992) The mutations for aprE high expression in B.subtilis Ki-2-132hpr mutant. Ann. Rep. of Institute of Genetics of Chinese Academy of Sciences. Vol12:13-14. Beijing Polytechnic University Press, Beijng, China. ### << Previous Next >> [ View All Member Spotlights ] |
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